⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868908 | 0.82 | LMNA (0.36) | — | |
| SCHEMBL9946998 | 0.63 | HSD17B10 (0.33) | — | |
| SCHEMBL4248767 | 0.59 | — | — | |
| SCHEMBL6964664 | 0.59 | — | — | |
| SCHEMBL9894660 | 0.57 | — | — | |
| SCHEMBL21880660 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL23878844 | 0.57 | — | — | |
| SCHEMBL9895232 | 0.57 | — | — | |
| SCHEMBL16921977 | 0.57 | — | — | |
| SCHEMBL24925793 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205173-A1 | SUBSTITUTED PIPERIDINES AND SUBSTITUTED TETRAHYDROPYRIDINES AS IMMUNE-MODULATING COMPOUNDS | BLACKSMITH MEDICINES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023009642-A1 | PYRROLO[2,3-B]PYRIDINE PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009618-A1 | BICYCLIC PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO, INC. (US) | 2023-02-02 | — | — | WO | disclosed |