Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493153 | 0.87 | CYP3A4 (0.44) | POLBMEN1KMT2ATSHR | |
| SCHEMBL2493025 | 0.87 | CYP3A4 (0.44) | POLBMEN1KMT2ATSHR | |
| SCHEMBL2498089 | 0.86 | POLB (0.42) | POLBMEN1KMT2ATSHRTDP1 | |
| SCHEMBL14311053 | 0.85 | POLB (0.38) | POLBMEN1KMT2ATSHRTDP1 | |
| SCHEMBL2490786 | 0.84 | LPAR3 (0.44) | POLBMEN1KMT2AKCNH2 | |
| SCHEMBL2494184 | 0.84 | LPAR3 (0.44) | POLBMEN1KMT2AKCNH2 | |
| SCHEMBL12191705 | 0.82 | CYP3A4 (0.39) | POLBMEN1KMT2A | |
| SCHEMBL12191704 | 0.79 | LPAR3 (0.40) | POLBMEN1KMT2AKCNH2 | |
| SCHEMBL2494369 | 0.77 | LPAR3 (0.48) | KCNH2 | |
| SCHEMBL2491641 | 0.77 | LPAR3 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882694-B1 | OLIGOMERS AND POLYMERS OF THIOPHENE COMPOUNDS HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8030438-B2 | Thiophene compound having phosphoric ester and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-8030438-B2 | Thiophene compound having phosphoric ester and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20100019229-A1 | Thiophene compound having phosphoric ester and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100019229-A1 | Thiophene compound having phosphoric ester and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-1882694-A1 | THIOPHENE COMPOUND HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-01-30 | — | — | EP | disclosed |
| US-7307037-B2 | Metallic catalysts for chemo-, regio- and stereoselective reactions, and corresponding precursors | CHEMI S.P.A. (IT) | 2007-12-11 | — | — | US | disclosed |
| US-20050107248-A1 | Metallic catalysts for chemo-, regio-and stereoselective reactions, and corresponding precursors | CHEMI S.P.A. (IT) | 2005-05-19 | — | — | US | disclosed |
| EP-1490173-A2 | METALORGANIC CATALYSTS FOR CHEMO-, REGIO- AND STEREOSELECTIVE REACTIONS, AND CORRESPONDING PRECURSORS | CHEMI S.p.A. (IT) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003074169-A2 | METALORGANIC CATALYSTS FOR CHEMO-, REGIO- AND STEREOSELECTIVE REACTIONS, AND CORRESPONDING PRECURSORS | CHEMI S.P.A. (IT) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100019229-A1 | Thiophene compound having phosphoric ester and process for producing the same | RRP12, NR2E1, TST | POLB 1838/4885MEN1 4275/4885KMT2A 4579/4885 |
| US-20050107248-A1 | Metallic catalysts for chemo-, regio-and stereoselective reactions, and corresponding precursors | PHOSPHO1, OSTC, MAS1 | POLB 408/4885MEN1 465/4885KMT2A 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.