Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249330 | 1.00 | NPSR1 (0.51) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL252478 | 0.89 | MAPT (0.64) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL252479 | 0.89 | MAPT (0.64) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL253009 | 0.88 | CDC7 (0.49) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL249121 | 0.88 | MAPT (0.52) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL249122 | 0.88 | MAPT (0.52) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL8513536 | 0.86 | CDC7 (0.45) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL247678 | 0.86 | CDC7 (0.45) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL246096 | 0.85 | CDC7 (0.44) | NPSR1MAPTCDC7RECQLLMNA | |
| SCHEMBL249527 | 0.85 | CDC7 (0.46) | NPSR1MAPTCDC7RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | claimed |
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | claimed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | claimed |
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | disclosed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CDC7, CDCA2, CDC5L | NPSR1 3921/4885MAPT 4131/4885CDC7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.