Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252478 | 1.00 | MAPT (0.64) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL249122 | 0.91 | MAPT (0.52) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL249121 | 0.91 | MAPT (0.52) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL249330 | 0.89 | NPSR1 (0.51) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL249331 | 0.89 | NPSR1 (0.51) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL253009 | 0.84 | CDC7 (0.49) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL8513536 | 0.82 | CDC7 (0.45) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL247678 | 0.82 | CDC7 (0.45) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL246096 | 0.82 | CDC7 (0.44) | MAPTNPSR1RECQLMAPK1TDP1 | |
| SCHEMBL249527 | 0.82 | CDC7 (0.46) | MAPTNPSR1RECQLMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | claimed |
| EP-2588478-A1 | AZAINDOLE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | disclosed |
| WO-2012002568-A1 | AZAINDOLE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CDC7, CDCA2, CDC5L | MAPT 4131/4885NPSR1 3921/4885RECQL 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.