Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746426 | 0.92 | TDP1 (0.41) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL19948710 | 0.92 | TDP1 (0.41) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL1760150 | 0.81 | HDAC1 (0.49) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL31511027 | 0.81 | TDP1 (0.46) | TDP1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL1929771 | 0.78 | SIGMAR1 (0.52) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL15262995 | 0.78 | PTGER4 (0.46) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL205459 | 0.78 | CA1 (0.45) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL24746443 | 0.78 | CA1 (0.45) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL29925130 | 0.78 | CA1 (0.45) | TDP1MEN1KMT2AGAACA1 | |
| SCHEMBL29891357 | 0.78 | CA1 (0.45) | TDP1MEN1KMT2AGAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119558-A1 | PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF | Incyte Corporation (US) | 2023-01-18 | — | — | EP | disclosed |