Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240742 | 1.00 | KCNH2 (0.47) | KCNH2FFAR1MAOBAKR1B1SPHK2 | |
| SCHEMBL24933800 | 0.85 | KCNH2 (0.44) | KCNH2FFAR1MAOBAKR1B1PARP10 | |
| SCHEMBL24933349 | 0.84 | GSTP1 (0.50) | FFAR1MAOBAKR1B1XDHPARP10 | |
| SCHEMBL24933666 | 0.84 | KCNH2 (0.48) | KCNH2FFAR1MAOBSPHK2ADAMTS4 | |
| SCHEMBL24933492 | 0.83 | MAOB (0.47) | FFAR1MAOBFFAR4PARP10PARP15 | |
| SCHEMBL30240735 | 0.83 | MAOB (0.40) | FFAR1MAOBFFAR4PARP10PARP15 | |
| SCHEMBL24933521 | 0.83 | MAOB (0.40) | FFAR1MAOBFFAR4PARP10PARP15 | |
| SCHEMBL24933641 | 0.82 | MAOB (0.39) | FFAR1MAOBFFAR4PARP10PARP15 | |
| SCHEMBL24933639 | 0.82 | NMT1 (0.40) | FFAR1MAOBFFAR4PARP10PARP15 | |
| SCHEMBL30240668 | 0.82 | MAOB (0.39) | FFAR1MAOBFFAR4PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |