Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240735 | 0.90 | MAOB (0.40) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL24933521 | 0.90 | MAOB (0.40) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL30240673 | 0.89 | PARP10 (0.39) | FFAR1MAOBHSD17B1HSD17B2DRD1 | |
| SCHEMBL24933799 | 0.89 | PARP10 (0.39) | FFAR1MAOBHSD17B1HSD17B2DRD1 | |
| SCHEMBL24933641 | 0.89 | MAOB (0.39) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL30240668 | 0.89 | MAOB (0.39) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL24933222 | 0.86 | PRKAB2 (0.44) | MAOBHSD17B1HSD17B2PARP10 | |
| SCHEMBL30240675 | 0.86 | HSD17B1 (0.41) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL24933406 | 0.86 | HSD17B1 (0.41) | FFAR1MAOBHSD17B1HSD17B2GYS1 | |
| SCHEMBL24933735 | 0.84 | HSD17B1 (0.41) | MAOBHSD17B1HSD17B2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |