Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.38 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240787 | 1.00 | HSD17B1 (0.38) | HSD17B1HSD17B2MOGAT2HDAC1HDAC6 | |
| SCHEMBL24933881 | 0.89 | HSD17B1 (0.38) | HSD17B1HSD17B2MOGAT2HDAC1HDAC6 | |
| SCHEMBL24933706 | 0.88 | PARP10 (0.39) | HSD17B1HSD17B2HDAC1HDAC6DHODH | |
| SCHEMBL24933809 | 0.88 | HSD17B1 (0.38) | HSD17B1HSD17B2HDAC1HDAC6PARP1 | |
| SCHEMBL24933226 | 0.83 | PPARD (0.40) | HSD17B1HSD17B2MOGAT2DHODHCDK5 | |
| SCHEMBL30240779 | 0.82 | PARP10 (0.51) | DHODHPDE10APARP10 | |
| SCHEMBL24933620 | 0.82 | PARP10 (0.51) | DHODHPDE10APARP10 | |
| SCHEMBL24932971 | 0.81 | KDM4E (0.38) | HSD17B1HSD17B2DHODHPARP1 | |
| SCHEMBL30240745 | 0.81 | HSD17B1 (0.40) | HSD17B1HSD17B2HDAC1HDAC6DHODH | |
| SCHEMBL30240672 | 0.81 | KDM4E (0.38) | HSD17B1HSD17B2DHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |