Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933256 | 0.89 | PDK2 (0.43) | HSD17B1HSD17B2MOGAT2PARP1BRD4 | |
| SCHEMBL24933847 | 0.87 | CHEK1 (0.46) | HSD17B1HSD17B2MOGAT2PARP1BRD4 | |
| SCHEMBL24933418 | 0.84 | MOGAT2 (0.41) | HSD17B1HSD17B2MOGAT2PARP1BRD4 | |
| SCHEMBL24932951 | 0.84 | CHEK1 (0.48) | MOGAT2PARP1PDK2CHEK2CHEK1 | |
| SCHEMBL24932956 | 0.84 | FYN (0.45) | HSD17B1HSD17B2PARP1BRD4BRD1 | |
| SCHEMBL24933007 | 0.83 | PPARD (0.44) | HSD17B1HSD17B2FFAR4 | |
| SCHEMBL24933053 | 0.82 | KDM4E (0.44) | HSD17B1HSD17B2PARP1CHEK1 | |
| SCHEMBL24933352 | 0.82 | MAOB (0.42) | HSD17B1HSD17B2PARP1FFAR4FFAR1 | |
| SCHEMBL24932990 | 0.82 | HSD17B1 (0.36) | HSD17B1HSD17B2MOGAT2FFAR4PDK2 | |
| SCHEMBL24933349 | 0.80 | GSTP1 (0.50) | HSD17B1HSD17B2CHEK2CNR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |