Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933475 | 0.79 | PARP10 (0.42) | MAOBPARP10GSTP1HDAC3PARP1 | |
| SCHEMBL24933352 | 0.76 | MAOB (0.42) | MAOBPARP10GSTP1FFAR1HDAC3 | |
| SCHEMBL24933199 | 0.73 | MAOB (0.46) | MAOBPARP10PARP15FFAR1ALDH1A1 | |
| SCHEMBL30240807 | 0.73 | MAOB (0.46) | MAOBPARP10PARP15FFAR1ALDH1A1 | |
| SCHEMBL24932976 | 0.72 | MAOB (0.52) | MAOBPARP10PARP15PARP14HDAC3 | |
| SCHEMBL30240782 | 0.72 | MAOB (0.52) | MAOBPARP10PARP15PARP14HDAC3 | |
| SCHEMBL30240765 | 0.72 | MAOB (0.47) | MAOBPARP10GSTP1PARP15PARP14 | |
| SCHEMBL24933362 | 0.72 | MAOB (0.47) | MAOBPARP10GSTP1PARP15PARP14 | |
| SCHEMBL24933615 | 0.72 | MAOB (0.60) | MAOBFFAR1FFAR4MAPTMAOA | |
| SCHEMBL24933349 | 0.71 | GSTP1 (0.50) | MAOBPARP10GSTP1FFAR1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |