SCHEMBL2493537

SCHEMBL2493537

C=CCc1cc(O)c(O)c(O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 2/20 0.63
PARP1 P09874 1/20 0.63
XDH P47989 1/20 0.61
TNKS2 Q9H2K2 1/20 0.58
GABRA1 P14867 5/20 0.54
GABRB2 P47870 5/20 0.54
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 2/20 0.54
GAA P10253 2/20 0.54
MAPT P10636 2/20 0.54
CNR1 P21554 2/20 0.54
CNR2 P34972 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH2 P05091 1/20 0.54
AKR1B1 P15121 1/20 0.54
HPGD P15428 1/20 0.54
PPARG P37231 1/20 0.54
PPARD Q03181 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8118653 0.89 TNKS (0.79) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL9319191 0.87 TNKS (0.56) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL31518908 0.85 TNKS (0.54) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL31518888 0.85 TNKS (0.54) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL17969003 0.83 XDH (0.59) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL18338811 0.82 TNKS (0.84) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL28430099 0.82 TNKS (0.51) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL30106410 0.82 TNKS (0.84) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL17546624 0.80 TNKS (0.68) TNKSPARP1XDHTNKS2GABRA1
SCHEMBL19677147 0.79 TNKS (0.66) TNKSPARP1XDHTNKS2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591769-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN claimed
CN-116425613-A Synthesis method of 5-allyl pyrogallol 苏州当量生物医药有限公司 2023-07-14 CN claimed
US-20230001046-A1 BIOCOMPATIBLE ADHESIVES AND METHODS OF MANUFACTURE THEREOF GOVERNING COUNCIL UNIV TORONTO (CA) 2023-01-05 US claimed
WO-2022261791-A1 AMPHIPHILIC OLIGOMERS AND SELF-ASSEMBLING HYDROGELS FORMED THEREFROM THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2022-12-22 WO claimed
US-20220395608-A1 WATER SOLUBLE BIOADHESIVES GOVERNING COUNCIL UNIV TORONTO (CA) 2022-12-15 US claimed
WO-2021119855-A1 WATER SOLUBLE BIOADHESIVES THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-06-24 WO claimed
US-4172960-A ETHERIFICATION, DEETHERIFICATION, DIALKYLATION FISONS LIMITED (GB) 1979-10-30 US claimed
US-20250090480-A1 UNIQUE ANALOGS OF NATURAL LIGNANS USEFUL FOR TREATING TRIPLE NEGATIVE BREAST CANCER UNIV KENTUCKY RES FOUND (US) 2025-03-20 US disclosed
CN-119591769-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN disclosed
WO-2024237320-A1 MEDICAL POLYMER COMPOSITION AND MEDICAL ADHESIVE CONTAINING SAME 東洋紡株式会社 2024-11-21 WO disclosed
WO-2024237321-A1 METHOD FOR CURING POLYMER COMPOSITION IN CONTACT WITH MEDICAL SUBSTRATE 東洋紡株式会社 2024-11-21 WO disclosed
CN-116425613-A Synthesis method of 5-allyl pyrogallol 苏州当量生物医药有限公司 2023-07-14 CN disclosed
CN-116425613-A Synthesis method of 5-allyl pyrogallol 苏州当量生物医药有限公司 2023-07-14 CN disclosed
WO-2011106630-A2 CHRYSOPHAENTIN ANTIMICROBIAL COMPOUNDS THAT INHIBIT FTSZ PROTEIN THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2011-09-01 WO disclosed
US-5779906-A Method of removing heavy metal ions from a liquid with chemically active ceramic compositions with a pyrogallol moiety SYRACUSE UNIVERSITY (US) 1998-07-14 US disclosed
US-5624881-A Chemically active ceramic compositions with a pyrogallol moiety SYRACUSE UNIVERSITY (US) 1997-04-29 US disclosed
WO-1996009885-A1 CHEMICALLY ACTIVE CERAMIC COMPOSITIONS WITH A PYROGALLOL MOIETY SYRACUSE UNIVERSITY (US) 1996-04-04 WO disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4172960-A ETHERIFICATION, DEETHERIFICATION, DIALKYLATION FISONS LIMITED (GB) 1979-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250090480-A1 UNIQUE ANALOGS OF NATURAL LIGNANS USEFUL FOR TREATING TRIPLE NEGATIVE BREAST CANCER BRCA1, GALK1, BRAP TNKS 315/4885PARP1 351/4885XDH 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.