Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936039 | 0.84 | HPGD (0.44) | PPARGPPARAHPGDNLRP1NPSR1 | |
| SCHEMBL25063933 | 0.84 | MRGPRX4 (0.40) | LMNAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24934759 | 0.82 | FFAR1 (0.40) | PPARGKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL24935185 | 0.81 | KMT2A (0.50) | TDP1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL20231597 | 0.80 | PPARG (0.49) | PPARGPPARAHPGDNLRP1NPSR1 | |
| SCHEMBL20225799 | 0.79 | HPGD (0.48) | PPARGPPARAHPGDNLRP1NPSR1 | |
| SCHEMBL25063926 | 0.77 | KDM4E (0.42) | SMN1; SMN2LMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL20225796 | 0.76 | THRA (0.49) | PPARGPPARAHPGDMAPTSMN1; SMN2 | |
| SCHEMBL10717259 | 0.76 | TDP1 (0.64) | MAPTSMN1; SMN2TDP1TSHRMEN1 | |
| SCHEMBL24935582 | 0.76 | ACACB (0.38) | MAPTSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |