Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688929 | 0.96 | HCAR2 (0.49) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL12413622 | 0.92 | HCAR2 (0.46) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL22535481 | 0.86 | MKNK1 (0.49) | HCAR2HPGDTSHRHCAR3KMT2A | |
| SCHEMBL22327725 | 0.84 | DAO (0.44) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL24759495 | 0.78 | HCAR2 (0.47) | HCAR2CCNA2CDK2CCNA1HCAR3 | |
| SCHEMBL21450656 | 0.75 | CCNA2 (0.42) | HCAR2CCNA2CDK2CCNA1HCAR3 | |
| SCHEMBL22535529 | 0.75 | NPC1 (0.35) | HPGDTSHR | |
| SCHEMBL15834440 | 0.75 | HCAR2 (0.49) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL1667926 | 0.75 | HCAR2 (0.47) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL17412842 | 0.73 | HCAR2 (0.47) | HCAR2DAOCCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | HCAR2 3916/4885DAO 3483/4885CCNA2 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.