Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.70 |
| ▸ | ITGAV | P06756 | 20/20 | 0.70 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860597 | 0.89 | ITGB3 (0.89) | ITGB3ITGAVITGB5 | |
| SCHEMBL2491160 | 0.82 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL2490010 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL2490009 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL2491273 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL852378 | 0.81 | ITGB3 (0.75) | ITGB3ITGAVITGB5 | |
| SCHEMBL2492095 | 0.81 | ITGB3 (0.86) | ITGB3ITGAVITGB5 | |
| SCHEMBL29207535 | 0.80 | ITGB3 (0.51) | ITGB3ITGAVITGB5 | |
| SCHEMBL2488336 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGB5 | |
| SCHEMBL29207492 | 0.80 | ITGB3 (0.51) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425010-B1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | ORTHO MCNEIL PHARM INC (US) | 2011-10-26 | — | — | EP | claimed |