Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152027 | 1.00 | CYP19A1 (0.45) | CYP19A1POLBNAMPTLMNAMAPT | |
| SCHEMBL24936696 | 1.00 | CYP19A1 (0.45) | CYP19A1POLBNAMPTLMNAMAPT | |
| SCHEMBL29211441 | 0.83 | CYP19A1 (0.45) | CYP19A1POLBLMNAMAPTMAPK1 | |
| SCHEMBL24937323 | 0.83 | CYP19A1 (0.45) | CYP19A1POLBLMNAMAPTMAPK1 | |
| SCHEMBL584760 | 0.83 | ALDH1A1 (0.52) | LMNAMAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL2384186 | 0.83 | ALDH1A1 (0.52) | LMNAMAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL24936695 | 0.83 | CYP19A1 (0.45) | CYP19A1POLBLMNAMAPTMAPK1 | |
| SCHEMBL584761 | 0.83 | ALDH1A1 (0.52) | LMNAMAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL12437265 | 0.80 | TDP1 (0.46) | POLBLMNAMAPTMAOBKDM4E | |
| SCHEMBL15409086 | 0.80 | HTT (0.53) | POLBMAPTRAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |