Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 7/20 | 1.00 |
| ▸ | OSBP | P22059 | 6/20 | 1.00 |
| ▸ | RORC | P51449 | 5/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.84 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.84 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.84 |
| ▸ | USP2 | O75604 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.84 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.84 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.80 |
| ▸ | CRYAB | P02511 | 1/20 | 0.76 |
| ▸ | HMGCR | P04035 | 1/20 | 0.76 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.76 |
| ▸ | ITGAV | P06756 | 1/20 | 0.76 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.76 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.76 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.75 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.72 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042866 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL6391967 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL288494 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL159618 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL23960515 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL13076858 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL1176969 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL22095720 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL22559557 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A | |
| SCHEMBL288733 | 1.00 | NR1H3 (1.00) | NR1H3OSBPRORCGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027864-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS | MODERNATX, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027864-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS | LCP2, CD14, MYD88 | NR1H3 633/4885OSBP 251/4885RORC 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.