SCHEMBL24937951

SCHEMBL24937951

C=CC(=O)OCCCCOc1ccc(CCc2ccc(C(=O)Oc3ccc(OC(=O)c4ccc(OC(=O)c5ccc(OCCCCOC(=O)C=C)cc5)cc4)c(C)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.43
MAPT P10636 4/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
KMT2A Q03164 2/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
PRSS1 P07477 1/20 0.39
ACR P10323 1/20 0.39
HTT P42858 2/20 0.38
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23848138 0.96 THRB (0.47) THRBMAPTNPC1LMNACYP1A2
SCHEMBL12794265 0.96 NPC1 (0.44) THRBMAPTNPC1LMNACYP1A2
SCHEMBL20883271 0.96 NPC1 (0.44) THRBMAPTNPC1LMNACYP1A2
SCHEMBL16425803 0.96 NPC1 (0.44) THRBMAPTNPC1LMNACYP1A2
SCHEMBL18803342 0.96 NPC1 (0.44) THRBMAPTNPC1LMNACYP1A2
SCHEMBL14000686 0.95 THRB (0.45) THRBMAPTNPC1LMNACYP1A2
SCHEMBL22430188 0.95 THRB (0.45) THRBMAPTNPC1LMNACYP1A2
SCHEMBL15149978 0.95 THRB (0.45) THRBMAPTNPC1LMNACYP1A2
SCHEMBL13944904 0.95 NPC1 (0.45) THRBMAPTNPC1LMNACYP1A2
SCHEMBL23395820 0.95 THRB (0.48) THRBMAPTNPC1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028048-A1 REFLECTION FILM, WINDSHIELD GLASS, AND HEAD-UP DISPLAY SYSTEM FUJIFILM CORPORATION (JP) 2023-01-26 US disclosed