Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733732 | 0.91 | KCNH2 (0.49) | CNR2KCNH2 | |
| SCHEMBL14855325 | 0.91 | KCNH2 (0.49) | CNR2KCNH2 | |
| SCHEMBL5013428 | 0.89 | KCNH2 (0.46) | CNR2KCNH2 | |
| SCHEMBL7272839 | 0.84 | HDAC6 (0.44) | KCNH2 | |
| SCHEMBL30686184 | 0.80 | GRIN2D (0.43) | CNR2KCNH2 | |
| SCHEMBL9561425 | 0.78 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL8857306 | 0.77 | TSHR (0.43) | HRH3 | |
| SCHEMBL5542097 | 0.76 | SIGMAR1 (0.57) | KCNH2ALOX5 | |
| SCHEMBL5542605 | 0.76 | SIGMAR1 (0.57) | KCNH2ALOX5 | |
| SCHEMBL22919812 | 0.76 | MAPT (0.42) | CNR2KCNH2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119552-A1 | REGULATING CHIMERIC ANTIGEN RECEPTORS | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |