Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710126 | 0.92 | CTSV (0.49) | CTSBCTSSCTSVCTSLCTSK | |
| Hydrochloric Acid SCHEMBL29179549 | 0.84 | CTSV (0.40) | CTSBCTSSCTSVCTSLCTSK | |
| Hydrochloric Acid SCHEMBL29179546 | 0.84 | CTSV (0.40) | CTSBCTSSCTSVCTSLCTSK | |
| Hydrochloric Acid SCHEMBL29179551 | 0.84 | CTSV (0.40) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL24939499 | 0.84 | CTSV (0.42) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL29179543 | 0.81 | CTSV (0.38) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL29179542 | 0.81 | CTSV (0.38) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL29179545 | 0.81 | CTSV (0.38) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL24710291 | 0.80 | CTSV (0.47) | CTSBCTSSCTSVCTSLCTSK | |
| SCHEMBL24710290 | 0.80 | CTSV (0.47) | CTSBCTSSCTSVCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024012-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024012-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | CTSB 15/4885CTSS 25/4885CTSV 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.