Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24938747 | 0.90 | DDB1 (0.46) | DDB1CRBNIDO1HTR1ADRD2 | |
| SCHEMBL24938749 | 0.87 | DDB1 (0.45) | DDB1CRBNIDO1 | |
| SCHEMBL24938748 | 0.87 | DDB1 (0.42) | DDB1CRBN | |
| SCHEMBL23117797 | 0.85 | CRBN (0.55) | DDB1CRBN | |
| SCHEMBL31426050 | 0.85 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL23117077 | 0.85 | DDB1 (0.43) | DDB1CRBNIDO1HTR1ADRD2 | |
| SCHEMBL23115253 | 0.85 | CRBN (0.43) | DDB1CRBN | |
| SCHEMBL23115219 | 0.84 | CRBN (0.54) | DDB1CRBNIDO1HTR1AHTR2A | |
| SCHEMBL26158807 | 0.84 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL23640504 | 0.84 | DDB1 (0.42) | DDB1CRBNIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001028-A1 | HETEROARYL-3-PIPERIDINEDIONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |