Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435870 | 1.00 | MEN1 (0.48) | MEN1KMT2ACASR | |
| SCHEMBL3435521 | 1.00 | MEN1 (0.48) | MEN1KMT2ACASR | |
| SCHEMBL10033208 | 0.96 | MEN1 (0.51) | MEN1KMT2ACASR | |
| SCHEMBL560467 | 0.96 | MEN1 (0.51) | MEN1KMT2ACASR | |
| SCHEMBL17972913 | 0.82 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL28369492 | 0.82 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL17533339 | 0.81 | EPHX1 (0.44) | — | |
| SCHEMBL17533351 | 0.81 | EPHX1 (0.44) | — | |
| SCHEMBL17533347 | 0.81 | EPHX1 (0.44) | — | |
| SCHEMBL17533286 | 0.81 | EPHX1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152651-B1 | THERAPEUTIC COMPOUNDS | PHARMACOFORE INC (US) | 2012-01-04 | — | — | EP | disclosed |