Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369492 | 1.00 | MEN1 (0.45) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL18272207 | 0.90 | ALDH1A1 (0.50) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL17973023 | 0.86 | EPHX1 (0.43) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL3435521 | 0.82 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL3435870 | 0.82 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL249390 | 0.82 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL17533469 | 0.80 | EPHX1 (0.44) | LMNA | |
| SCHEMBL17533347 | 0.80 | EPHX1 (0.44) | LMNA | |
| SCHEMBL17533339 | 0.80 | EPHX1 (0.44) | LMNA | |
| SCHEMBL17533286 | 0.80 | EPHX1 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108483-B | Preparation method and intermediate of 2- [ 1-cycloalkylethyl ] phenol | 四川海思科制药有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-107074675-B | Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| WO-2016119758-A1 | METHOD FOR PREPARING CHIRAL 2-[1-CYCLOPROPYLETHYL]-6-ISOPROPYL-PHENOL | 四川海思科制药有限公司 | 2016-08-04 | — | — | WO | disclosed |
| WO-2016119757-A1 | METHOD FOR PREPARING 2-[1-CYCLOALKYLETHYL] PHENOL AND INTERMEDIATE THEREOF | 四川海思科制药有限公司 | 2016-08-04 | — | — | WO | disclosed |