Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | LCAT | P04180 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29179565 | 0.99 | CASP3 (0.39) | CASP3CASP8CASP1CASP9CYP2D6 | |
| Hydrochloric Acid SCHEMBL29179568 | 0.99 | CASP3 (0.39) | CASP3CASP8CASP1CASP9CYP2D6 | |
| Hydrochloric Acid SCHEMBL29179573 | 0.99 | CASP3 (0.39) | CASP3CASP8CASP1CASP9CYP2D6 | |
| Hydrochloric Acid SCHEMBL30277121 | 0.99 | CASP3 (0.39) | CASP3CASP8CASP1CASP9CYP2D6 | |
| SCHEMBL29179606 | 0.87 | CASP3 (0.38) | CASP3CASP8CASP1CASP9CYP2D6 | |
| SCHEMBL29179613 | 0.87 | CASP3 (0.38) | CASP3CASP8CASP1CASP9CYP2D6 | |
| SCHEMBL29179610 | 0.87 | CASP3 (0.38) | CASP3CASP8CASP1CASP9CYP2D6 | |
| SCHEMBL29179587 | 0.82 | CASP3 (0.41) | CASP3CASP8CASP1CASP9CASP6 | |
| SCHEMBL24710762 | 0.82 | CASP3 (0.41) | CASP3CASP8CASP1CASP9CASP6 | |
| SCHEMBL29179591 | 0.82 | CASP3 (0.41) | CASP3CASP8CASP1CASP9CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230024012-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024012-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | CASP3 239/4885CASP8 903/4885CASP1 194/4885 |
| US-11708348-B2 | Protease inhibitors for treatment of coronavirus infections | ACE, ACE2, TMPRSS2 | CASP3 239/4885CASP8 903/4885CASP1 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.