Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939664 | 0.86 | AR (0.60) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24939661 | 0.83 | AR (0.53) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30938122 | 0.79 | AR (0.55) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27410904 | 0.77 | MAPT (0.46) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18674647 | 0.74 | AR (0.66) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27315641 | 0.74 | AR (0.62) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24939659 | 0.73 | AR (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18674614 | 0.73 | AR (0.71) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18674683 | 0.71 | AR (0.64) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27413115 | 0.70 | AR (0.78) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001028-A1 | HETEROARYL-3-PIPERIDINEDIONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |