Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939664 | 0.87 | AR (0.60) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL30938128 | 0.86 | AR (0.56) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL18674683 | 0.83 | AR (0.64) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL1473981 | 0.81 | AR (0.71) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL18674648 | 0.79 | RAB9A (0.74) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL26979822 | 0.78 | AR (0.57) | ARRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL3012588 | 0.78 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1MAPK1LMNA | |
| SCHEMBL12601866 | 0.78 | AR (0.94) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL18674650 | 0.78 | AR (0.74) | ARRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL6629014 | 0.77 | AR (1.00) | ARRAB9ASMN1; SMN2NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086361-A1 | MOLECULAR GLUE DEGRADER COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2024-04-25 | — | — | WO | disclosed |