SCHEMBL24939702

SCHEMBL24939702

O=C(O)C1CCC(CN2C(=O)C3=C(CCCC3)C2=O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
PLG P00747 1/20 0.42
PLAT P00750 1/20 0.42
BACE1 P56817 1/20 0.41
BACE2 Q9Y5Z0 1/20 0.41
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
CREBBP Q92793 1/20 0.37
KAT2A Q92830 1/20 0.37
KAT2B Q92831 1/20 0.37
DUSP3 P51452 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ANPEP P15144 1/20 0.35
ENPEP Q07075 1/20 0.35
TRPA1 O75762 4/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1B1 Q16678 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31236808 0.80 DUSP3 (0.45) LMNAPLGPLATBACE1BACE2
SCHEMBL24939701 0.80 LMNA (0.44) LMNAPLGPLATBACE1BACE2
SCHEMBL535579 0.80 PLG (0.47) LMNAPLGPLATBACE1BACE2
SCHEMBL16552327 0.80 PLG (0.47) LMNAPLGPLATBACE1BACE2
SCHEMBL7582928 0.76 CREBBP (0.50) BACE1BACE2CREBBPKAT2AKAT2B
SCHEMBL30657546 0.76 CREBBP (0.50) BACE1BACE2CREBBPKAT2AKAT2B
SCHEMBL7582920 0.76 CREBBP (0.50) BACE1BACE2CREBBPKAT2AKAT2B
SCHEMBL30657547 0.76 CREBBP (0.50) BACE1BACE2CREBBPKAT2AKAT2B
SCHEMBL159817 0.75 LMNA (0.46) LMNAPLGPLATBACE1BACE2
SCHEMBL890390 0.75 LMNA (0.46) LMNAPLGPLATBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230022129-A1 RESIST MATERIAL AND PATTERNING PROCESS GFER, LBR, PCNA LMNA 1223/4885PLG 4225/4885PLAT 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.