Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589477 | 0.96 | GRM2 (0.32) | GRM2DRD2DRD3HTR1A | |
| SCHEMBL24940297 | 0.88 | — | — | |
| SCHEMBL21589631 | 0.86 | GRM2 (0.32) | GRM2DRD2 | |
| SCHEMBL21589585 | 0.85 | RARB (0.32) | — | |
| SCHEMBL21589780 | 0.85 | — | — | |
| SCHEMBL21589627 | 0.84 | — | — | |
| SCHEMBL21589522 | 0.84 | — | — | |
| SCHEMBL21589468 | 0.84 | NR1H4 (0.33) | — | |
| SCHEMBL21589672 | 0.83 | PDK1 (0.30) | — | |
| SCHEMBL23481412 | 0.83 | GRM2 (0.32) | GRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-01-18 | — | — | EP | disclosed |