Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397718 | 0.81 | PTGS2 (0.35) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL3363212 | 0.73 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL2581522 | 0.70 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL13560371 | 0.69 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL12160562 | 0.67 | MEN1 (0.38) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL822693 | 0.66 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13907677 | 0.65 | KMT2A (0.54) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5537251 | 0.65 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL171304 | 0.65 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL12510434 | 0.64 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |