Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 18/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24941089 | 1.00 | NT5E (0.60) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL21882976 | 0.88 | NT5E (0.59) | NT5E | |
| SCHEMBL21839500 | 0.88 | NT5E (0.59) | NT5E | |
| SCHEMBL24940218 | 0.86 | NT5E (0.49) | NT5E | |
| SCHEMBL23907542 | 0.85 | NT5E (0.44) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL29893560 | 0.82 | ADORA2A (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24941203 | 0.82 | ADORA2A (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24941247 | 0.82 | NT5E (0.55) | NT5E | |
| SCHEMBL24940138 | 0.81 | NT5E (0.46) | NT5E | |
| SCHEMBL24940971 | 0.80 | NT5E (0.50) | NT5EADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033360-A1 | COMPOUNDS AS CD73 INHIBITORS | BIOARDIS LLC | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230033360-A1 | COMPOUNDS AS CD73 INHIBITORS | ENTPD5, ENTPD1, NT5E | NT5E 3/4885ADORA3 44/4885ADORA2A 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.