Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24941203 | 1.00 | ADORA2A (0.52) | ADORA2AADORA3ADORA2BADORA1MEN1 | |
| SCHEMBL21882976 | 0.84 | NT5E (0.59) | — | |
| SCHEMBL21839500 | 0.84 | NT5E (0.59) | — | |
| SCHEMBL29893392 | 0.84 | ADORA3 (0.44) | ADORA2AADORA3ADORA2BADORA1MEN1 | |
| SCHEMBL24941095 | 0.84 | ADORA3 (0.44) | ADORA2AADORA3ADORA2BADORA1MEN1 | |
| SCHEMBL24941089 | 0.82 | NT5E (0.60) | ADORA2AADORA3ADORA1 | |
| SCHEMBL23907542 | 0.82 | NT5E (0.44) | ADORA2AADORA3ADORA1 | |
| SCHEMBL24940140 | 0.82 | NT5E (0.60) | ADORA2AADORA3ADORA1 | |
| SCHEMBL22571948 | 0.75 | ADORA3 (0.52) | ADORA2AADORA3ADORA2BADORA1MEN1 | |
| SCHEMBL22571969 | 0.75 | ADORA3 (0.56) | ADORA2AADORA3ADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055026-A1 | COMPOUNDS AS CD73 INHIBITORS | Bioardis LLC (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114945578-A | Compounds as CD73 inhibitors | 博奥阿迪斯生物科技公司 | 2022-08-26 | — | — | CN | disclosed |