Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 1.00 |
| ▸ | CA2 | P00918 | 8/20 | 0.71 |
| ▸ | CA12 | O43570 | 7/20 | 0.71 |
| ▸ | CA9 | Q16790 | 7/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494083 | 1.00 | SIRT2 (1.00) | SIRT2CA2CA12CA9CA1 | |
| SCHEMBL30301787 | 0.94 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| SCHEMBL10620536 | 0.94 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| SCHEMBL10620538 | 0.94 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL347862 | 0.93 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 | 0.93 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL347861 | 0.93 | SIRT2 (0.88) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL453634 | 0.91 | SIRT2 (0.84) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL5418701 | 0.91 | SIRT2 (0.84) | SIRT2CA2CA12CA9CA1 | |
| 2-((Phenylimino)Methyl)Phenol SCHEMBL27996307 | 0.91 | SIRT2 (0.84) | SIRT2CA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014281-A1 | Use of inhibitors of sirtuins and/or ampk for the preparation of a medicament for the treatment of polyalanine diseases. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-01-14 | — | — | EP | claimed |
| WO-2008155390-A2 | USE OF INHIBITORS OF SIRTUINS AND/OR AMPK FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF POLYALANINE DISEASES. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-12-24 | — | — | WO | claimed |
| EP-1507837-B1 | SEGMENTED CURABLE TRANSFER TAPES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1507837-A1 | SEGMENTED CURABLE TRANSFER TAPES | 3M Innovative Properties Company (US) | 2005-02-23 | — | — | EP | claimed |
| WO-2003102102-A1 | SEGMENTED CURABLE TRANSFER TAPES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-11 | — | — | WO | claimed |
| US-20030221770-A1 | Segmented curable transfer tapes | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-04 | — | — | US | claimed |
| US-8030382-B2 | Polylactic acid composition | TEIJIN LIMITED (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-1508261-B1 | ELECTRONIC ASSEMBLY AND METHOD OF MAKING AN ELECTRONIC ASSEMBLY | 3M INNOVATIVE PROPERTIES CO (US) | 2010-09-22 | — | — | EP | disclosed |
| US-20100093888-A1 | POLYLACTIC ACID COMPOSITION | TEIJIN LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2116576-A1 | POLYLACTIC ACID COMPOSITION | Teijin Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7482201-B2 | Nanoparticle filled underfill | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-01-27 | — | — | US | disclosed |
| EP-2014281-A1 | Use of inhibitors of sirtuins and/or ampk for the preparation of a medicament for the treatment of polyalanine diseases. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008155390-A2 | USE OF INHIBITORS OF SIRTUINS AND/OR AMPK FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF POLYALANINE DISEASES. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-12-24 | — | — | WO | disclosed |
| US-20080108180-A1 | NANOPARTICLE FILLED UNDERFILL | 3M INNOVATIVE PROPERTIES COMPANY | 2008-05-08 | — | — | US | disclosed |
| US-7327039-B2 | Nanoparticle filled underfill | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| EP-1507837-B1 | SEGMENTED CURABLE TRANSFER TAPES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1508261-A1 | NANOPARTICLE FILLED UNDERFILL | 3M Innovative Properties Company (US) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003101164-A1 | NANOPARTICLE FILLED UNDERFILL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030221770-A1 | Segmented curable transfer tapes | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-04 | — | — | US | disclosed |
| US-20030218258-A1 | Nanoparticle filled underfill | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-27 | — | — | US | disclosed |