2-((Phenylimino)Methyl)Phenol

2-((Phenylimino)Methyl)Phenol

SCHEMBL453634

Oc1ccccc1C=Nc1ccccc1.[Pd]

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.84
CA12 O43570 7/20 0.64
CA2 P00918 7/20 0.64
CA9 Q16790 6/20 0.64
TSHR P16473 1/20 0.62
CA1 P00915 1/20 0.62
MAOB P27338 2/20 0.59
PABPC1 P11940 1/20 0.55
APOBEC3A P31941 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
KDM4E B2RXH2 2/20 0.53
MAPT P10636 3/20 0.52
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
MEN1 O00255 1/20 0.52
HPGD P15428 1/20 0.52
GFER P55789 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 1/20 0.50
RAD52 P43351 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-((Phenylimino)Methyl)Phenol SCHEMBL347862 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL347861 0.98 SIRT2 (0.88) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL5376364 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL27996307 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL1133042 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL5418701 0.96 SIRT2 (0.84) SIRT2CA12CA2CA9TSHR
2-((Phenylimino)Methyl)Phenol SCHEMBL28071396 0.92 SIRT2 (0.78) SIRT2CA12CA2CA9TSHR
SCHEMBL2494084 0.91 SIRT2 (1.00) SIRT2CA12CA2CA9TSHR
SCHEMBL2494083 0.91 SIRT2 (1.00) SIRT2CA12CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP claimed
CN-103080150-A Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KK 2013-05-01 CN claimed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO claimed
EP-2614091-B1 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2016-04-20 EP disclosed
CN-103080150-B Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 2015-09-02 CN disclosed
CN-103080150-B Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 2015-09-02 CN disclosed
US-8598288-B2 Catalyst for polymerization of norbornene monomers, method for producing norbornene polymer, method for producing norbornene copolymer, norbornene polymer and transition metal complex SHOWA DENKO K.K. (JP) 2013-12-03 US disclosed
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP disclosed
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP disclosed
CN-103080150-A Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KK 2013-05-01 CN disclosed
CN-103080150-A Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KK 2013-05-01 CN disclosed
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX SHOWA DENKO K.K. (JP) 2013-03-07 US disclosed
WO-2012033227-A3 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-08-16 WO disclosed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO disclosed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX NNMT, PPOX, DNMT1 SIRT2 1058/4885CA12 2079/4885CA2 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.