Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779221 | 0.88 | POLRMT (0.46) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL20960018 | 0.86 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL16708542 | 0.86 | POLRMT (0.51) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL16708594 | 0.85 | POLRMT (0.45) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL20960074 | 0.84 | POLRMT (0.59) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL19101844 | 0.79 | POLRMT (0.53) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL17106741 | 0.79 | POLRMT (0.47) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL17106862 | 0.79 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL20960073 | 0.78 | POLRMT (0.46) | POLRMTP2RY1P2RY2P2RY11RNASEL | |
| SCHEMBL23960102 | 0.78 | POLRMT (0.40) | POLRMTP2RY1P2RY2P2RY11RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122932-A1 | PYRROLO[1,2-F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |