Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30412030 | 0.98 | EPHX1 (0.59) | EPHX1HDAC1HDAC8AURKATAAR1 | |
| SCHEMBL4309679 | 0.95 | TAAR1 (0.60) | EPHX1HDAC1HDAC8AURKATAAR1 | |
| SCHEMBL30645023 | 0.90 | TAAR1 (0.62) | EPHX1HDAC1HDAC8AURKATAAR1 | |
| SCHEMBL185922 | 0.90 | TAAR1 (0.62) | EPHX1HDAC1HDAC8AURKATAAR1 | |
| SCHEMBL11755472 | 0.88 | HDAC1 (0.60) | EPHX1HDAC1HDAC8TAAR1ACP3 | |
| SCHEMBL18798841 | 0.87 | HDAC1 (0.71) | EPHX1HDAC1HDAC8AURKATAAR1 | |
| SCHEMBL11038774 | 0.86 | HDAC1 (0.59) | EPHX1HDAC1HDAC8TAAR1ACP3 | |
| SCHEMBL7150587 | 0.86 | MAPT (0.60) | EPHX1HDAC1HDAC8TAAR1 | |
| SCHEMBL11041817 | 0.85 | HDAC1 (0.58) | EPHX1HDAC1HDAC8TAAR1ACP3 | |
| SCHEMBL11038941 | 0.85 | HDAC1 (0.58) | EPHX1HDAC1HDAC8TAAR1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |