SCHEMBL2494471

SCHEMBL2494471

CCC(C)(C)c1[c]ccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP2A6 P11509 3/20 0.33
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
KEAP1 Q14145 1/20 0.32
SIGMAR1 Q99720 3/20 0.32
LMNA P02545 2/20 0.32
NR1I2 O75469 1/20 0.32
ADRA2A P08913 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502071 0.81 CYP2A6 (0.39) CYP2D6CYP1A2CYP2C19ALDH1A1CYP2A6
SCHEMBL7299472 0.77 CYP2A6 (0.41) CYP2D6CYP1A2CYP2C19ALDH1A1CYP2A6
SCHEMBL18242107 0.74 CYP2A6 (0.36) CYP1A2ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL456517 0.73 ALDH1A1 (0.39) CYP2D6CYP1A2CYP2C19ALDH1A1CYP2A6
SCHEMBL18243200 0.71 CYP2A6 (0.33) CYP1A2ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL2127614 0.71 ALDH1A1 (0.43) CYP2D6CYP1A2CYP2C19ALDH1A1CYP2A6
SCHEMBL18378094 0.70 ALDH1A1 (0.36) CYP1A2ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL18243967 0.70 CYP2A6 (0.32) CYP1A2ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL455640 0.69 CYP2A6 (0.39) CYP2D6CYP1A2CYP2C19ALDH1A1CYP2A6
SCHEMBL11137608 0.69 NR4A1 (0.38) CYP2D6CYP1A2CYP2C19ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8497334-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-30 US disclosed
US-20110245407-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed
CN-102206305-A Conjugated diene polymer,conjugated diene polymei composition, and method for producing conjugated diene polymer SUMITOMO CO LTD 2011-10-05 CN disclosed