Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945385 | 0.84 | MAPT (0.66) | LMNAMAPTTP53NPC1GAA | |
| SCHEMBL26687687 | 0.79 | TP53 (0.70) | LMNAMAPTTP53NPC1GAA | |
| SCHEMBL13236226 | 0.75 | TP53 (1.00) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL24943938 | 0.74 | TP53 (1.00) | LMNAMAPTTP53ALDH1A1 | |
| SCHEMBL24045328 | 0.74 | TP53 (0.71) | MAPTTP53 | |
| SCHEMBL24943939 | 0.73 | TP53 (0.81) | LMNAMAPTTP53ALDH1A1POLB | |
| SCHEMBL24045258 | 0.72 | MAPT (0.89) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL4215617 | 0.71 | PTGES (0.62) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL24045100 | 0.70 | MAPK1 (0.75) | MAPTTP53POLB | |
| SCHEMBL24045321 | 0.69 | MAPT (0.89) | LMNAMAPTTP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009347-A1 | COMPOUNDS FOR MODULATING EPITHELIAL 15-(S)-LIPOXYGENASE-2 AND METHODS OF USE FOR SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-02 | — | — | WO | disclosed |