Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698295 | 0.88 | GPR119 (0.62) | GPR119 | |
| SCHEMBL24945663 | 0.88 | GPR119 (0.62) | GPR119 | |
| SCHEMBL24945645 | 0.86 | GPR119 (0.49) | GPR119 | |
| SCHEMBL12740686 | 0.82 | GPR119 (0.82) | GPR119 | |
| SCHEMBL23744182 | 0.82 | GPR119 (0.47) | GPR119 | |
| SCHEMBL23744307 | 0.82 | GPR119 (0.47) | GPR119 | |
| SCHEMBL28539423 | 0.80 | GPR119 (0.78) | GPR119 | |
| SCHEMBL21564435 | 0.80 | GPR119 (0.78) | GPR119 | |
| SCHEMBL24945468 | 0.79 | CHRM2 (0.53) | — | |
| SCHEMBL941838 | 0.79 | GPR119 (0.57) | GPR119PRMT5YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010078-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2023-02-02 | — | — | WO | disclosed |