Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945920 | 1.00 | ACE (0.55) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL23463314 | 0.96 | ACE (0.52) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL22300308 | 0.96 | ACE (0.52) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL3817109 | 0.95 | PPARA (0.55) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL1517760 | 0.95 | PPARA (0.55) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL23447220 | 0.94 | ACE (0.49) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL24235725 | 0.92 | MEN1 (0.49) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL16478621 | 0.91 | ACE (0.55) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL22300883 | 0.91 | CTSS (0.53) | ACEKLK7KLK5PPARACTSS | |
| SCHEMBL17347936 | 0.91 | CTSS (0.53) | ACEKLK7KLK5PPARACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002452-A1 | PROCESS FOR PREPARATION OF TARGETING LIGANDS | Janssen Pharmaceuticals, Inc. (US) | 2023-01-26 | — | — | WO | disclosed |