Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.60 |
| ▸ | PARP14 | Q460N5 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119809 | 0.89 | KIF11 (0.70) | KIF11PARP14KDM4ETDO2MAPT | |
| SCHEMBL29177749 | 0.89 | KIF11 (0.50) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL51675 | 0.86 | PARP14 (0.49) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL32666064 | 0.85 | KIF11 (0.65) | KIF11PARP14KDM4ETDO2MAPT | |
| SCHEMBL29177771 | 0.85 | POLB (0.46) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL30021110 | 0.84 | ESR1 (0.47) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL20293634 | 0.84 | PARP14 (0.48) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL30332453 | 0.84 | HTR2B (0.46) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL30302649 | 0.84 | HTR2B (0.46) | KIF11PARP14TDO2HTR2BHTR5A | |
| SCHEMBL29177924 | 0.84 | ESR1 (0.47) | KIF11PARP14TDO2HTR2BHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523834-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |