Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415162 | 0.82 | ERN1 (0.50) | ERN1TRIM24TRIM33ESR1ESR2 | |
| SCHEMBL1464801 | 0.82 | ERN1 (0.50) | ERN1TRIM24TRIM33 | |
| SCHEMBL3070038 | 0.80 | ERN1 (0.39) | ERN1 | |
| SCHEMBL17451251 | 0.80 | ERN1 (0.54) | ERN1TRIM24TRIM33 | |
| SCHEMBL248719 | 0.76 | ERN1 (0.50) | ERN1 | |
| SCHEMBL29616071 | 0.75 | ERN1 (0.44) | ERN1TRIM24TRIM33ESR1ESR2 | |
| SCHEMBL2108906 | 0.75 | ERN1 (0.44) | ERN1TRIM24TRIM33 | |
| SCHEMBL206013 | 0.75 | ERN1 (0.44) | ERN1TRIM24TRIM33ESR1ESR2 | |
| SCHEMBL1057387 | 0.75 | ERN1 (0.44) | ERN1TRIM24TRIM33ESR1ESR2 | |
| SCHEMBL13448073 | 0.75 | ERN1 (0.48) | ERN1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| WO-2023000834-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE-6-CARBOXYLIC ACID COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| CN-113480534-B | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113480534-A | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药技术有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-107383024-B | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107383024-A | The class compound of fused tricyclic containing imidazoles and its application | 广州必贝特医药技术有限公司 | 2017-11-24 | — | — | CN | disclosed |