Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415162 | 0.90 | ERN1 (0.50) | ERN1TRIM24TRIM33 | |
| SCHEMBL248719 | 0.84 | ERN1 (0.50) | ERN1KDM4E | |
| SCHEMBL1057387 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33 | |
| SCHEMBL2108906 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33KDM4E | |
| SCHEMBL15179593 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33PIM1KDM4E | |
| SCHEMBL24947221 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33 | |
| SCHEMBL3562577 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33PIM1 | |
| SCHEMBL29616071 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33 | |
| SCHEMBL206013 | 0.82 | ERN1 (0.44) | ERN1TRIM24TRIM33 | |
| SCHEMBL3404206 | 0.82 | ERN1 (0.52) | ERN1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393277-B | 4-butyl polyhydroxy benzophenone compound derivative and application thereof | 山西医科大学 | 2023-01-03 | — | — | CN | claimed |
| CN-111393277-A | 4-butyl polyhydroxy benzophenone compound derivative and application thereof | 山西医科大学 | 2020-07-10 | — | — | CN | claimed |
| US-20200205541-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2020-07-02 | — | — | US | claimed |
| US-20130298933-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL (FR) | 2013-11-14 | — | — | US | claimed |
| EP-2358338-B1 | DYE, COMPRISING SPECIAL HALOGEN SUBSTITUTED PYROCATECHOL ALDEHYDES AND SPECIAL CH-ACIDIC COMPOUNDS | HENKEL AG & CO KGAA (DE) | 2013-10-16 | — | — | EP | claimed |
| EP-2358338-A2 | DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS | Henkel AG & Co. KGaA (DE) | 2011-08-24 | — | — | EP | claimed |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | claimed |
| WO-2010072511-A2 | DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2010-07-01 | — | — | WO | claimed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| US-RE50453-E1 | Indole derivatives as CFTR modulators | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| CN-119816484-A | Novel piperazine derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2025-04-11 | — | — | CN | disclosed |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2024-03-21 | — | — | US | disclosed |
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-02 | — | — | US | disclosed |
| US-20050143373-A1 | Benzodioxole derivatives | ALANINE ALEXANDER (FR) | 2005-06-30 | — | — | US | disclosed |
| US-6900227-B2 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |
| US-20040142922-A1 | Benzodioxole derivatives | HOFFMANN-LA ROCHE INC. | 2004-07-22 | — | — | US | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200205541-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | KRT18, TUBB4A, TUBB4B | ERN1 3359/4885TRIM24 562/4885TRIM33 441/4885 |
| US-20050143373-A1 | Benzodioxole derivatives | CNR2, CNR1, GPR119 | ERN1 4707/4885TRIM24 4782/4885TRIM33 4675/4885 |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ERN1 3304/4885TRIM24 3587/4885TRIM33 2781/4885 |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ERN1 3304/4885TRIM24 3587/4885TRIM33 2781/4885 |
| US-20040142922-A1 | Benzodioxole derivatives | CNR1, CNR2, GPR119 | ERN1 4069/4885TRIM24 4653/4885TRIM33 4768/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | ERN1 3094/4885TRIM24 4520/4885TRIM33 4337/4885 |
| US-20100300472-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND | KRT18, TUBB4A, TUBB4B | ERN1 3359/4885TRIM24 562/4885TRIM33 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.