Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12857109 | 0.78 | CES2 (0.48) | CES2CES1MAPTLMNAXBP1 | |
| SCHEMBL14613742 | 0.78 | F2 (0.33) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL29720126 | 0.78 | MEN1 (0.36) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL22271244 | 0.76 | KDM4E (0.38) | MAPTKMT2ALMNAATMSMN1; SMN2 | |
| SCHEMBL13349596 | 0.75 | MAPT (0.42) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL21064096 | 0.75 | CES2 (0.37) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL18381166 | 0.73 | MEN1 (0.38) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL19750242 | 0.73 | MAPT (0.33) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL18460837 | 0.72 | ATM (0.38) | CES2CES1MAPTMEN1KMT2A | |
| SCHEMBL28085607 | 0.72 | ATM (0.38) | CES2CES1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523834-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |