SCHEMBL24948349

SCHEMBL24948349

c1ccc(-c2ccccc2N(c2ccc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2)c2ccc(-c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
HDAC4 P56524 1/20 0.36
TNF P01375 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
PPARG P37231 7/20 0.34
PPARA Q07869 7/20 0.34
MAPK14 Q16539 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
PPARD Q03181 1/20 0.33
CYP1A2 P05177 1/20 0.33
PDE6D O43924 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24947299 1.00 KDM4E (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL19660651 1.00 KDM4E (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24948356 0.99 KDM4E (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24949509 0.98 KDM4E (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL21971560 0.94 KDM4E (0.38) KDM4EATML3MBTL1CA12CA1
SCHEMBL21974075 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24947986 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24948002 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1CA12CA1
SCHEMBL24946780 0.93 CA12 (0.36) KDM4EATML3MBTL1CA12CA1
SCHEMBL24948623 0.93 CA12 (0.36) KDM4EATML3MBTL1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed