Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991396 | 0.72 | TOP2A (0.42) | TOP2AACHELMNA | |
| SCHEMBL25861268 | 0.71 | TOP2A (0.41) | TOP2AACHE | |
| SCHEMBL22576366 | 0.71 | TOP2A (0.41) | TOP2AACHE | |
| SCHEMBL24949783 | 0.71 | TOP2A (0.36) | TOP2AACHE | |
| SCHEMBL24665880 | 0.68 | TOP2A (0.39) | TOP2AACHE | |
| SCHEMBL13039572 | 0.67 | TRPV4 (0.32) | LMNA | |
| SCHEMBL14384098 | 0.67 | CCR1 (0.40) | ACHELMNA | |
| SCHEMBL23404192 | 0.64 | TOP2A (0.39) | TOP2AACHELMNA | |
| SCHEMBL24863309 | 0.64 | CACNA1H (0.36) | TOP2AABL1BCR | |
| SCHEMBL21721601 | 0.64 | KDM4E (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006634-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-02 | — | — | WO | disclosed |