SCHEMBL2494971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2489493	0.75	HDAC4 (0.50)	MEN1KMT2AHDAC4HDAC2HDAC8
	SCHEMBL16097044	0.72	KMT2A (0.42)	MEN1KMT2ACRHR1ALDH1A1
	SCHEMBL15859646	0.72	MEN1 (0.64)	MEN1KMT2AUSP2ALDH1A1PABPC1
	SCHEMBL2495694	0.71	HDAC4 (0.43)	MEN1KMT2AHDAC4HDAC2HDAC8
	SCHEMBL2490777	0.71	PDE4B (0.42)	MEN1KMT2AUSP2ALDH1A1
	SCHEMBL15466179	0.71	RPS6KA2 (0.45)	MEN1KMT2ARPS6KA2
	SCHEMBL11096265	0.71	ABL1 (0.58)	HDAC4HDAC2HDAC8ABL1ABCB1
	SCHEMBL9959026	0.71	ABL1 (0.46)	HDAC4HDAC2HDAC8ABL1ABCB1
	SCHEMBL430965	0.71	ABL1 (0.46)	HDAC4HDAC2HDAC8ABL1ABCB1
	SCHEMBL7024625	0.71	ABL1 (0.46)	HDAC4HDAC2HDAC8ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.