SCHEMBL430965

SCHEMBL430965

COc1ccc(-c2cccc(COCc3cccc(-c4ccc(OC)cc4)c3-c3ccc(OC)cc3)c2-c2ccc(OC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.46
ABCB1 P08183 3/20 0.46
BCR P11274 3/20 0.46
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
ENPP1 P22413 1/20 0.42
BACE1 P56817 2/20 0.41
SYK P43405 3/20 0.41
AURKB Q96GD4 1/20 0.41
INCENP Q9NQS7 1/20 0.41
ESR2 Q92731 1/20 0.40
HTR7 P34969 1/20 0.39
APP P05067 2/20 0.39
HEXA P06865 1/20 0.38
HEXB P07686 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495694 0.90 HDAC4 (0.43) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL2489138 0.88 MAOB (0.40) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL2357517 0.85 ESR2 (0.41) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL2489493 0.85 HDAC4 (0.50) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL1974122 0.83 ABL1 (0.46) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL7024625 0.83 ABL1 (0.46) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL9959026 0.83 ABL1 (0.46) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL6409694 0.78 FFAR4 (0.54) FFAR1FFAR4
SCHEMBL3024594 0.78 FFAR1 (0.42) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL6408337 0.77 FFAR1 (0.40) HDAC4HDAC2HDAC8FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030065-A1 FLUORESCEIN POLYMER CONJUGATES ISI LIFE SCIENCES, INC. (US) 2018-02-01 US claimed
EP-3250197-A1 FLUORESCEIN POLYMER CONJUGATES Indicator Systems International, Inc. (US) 2017-12-06 EP claimed
WO-2016123244-A1 FLUORESCEIN POLYMER CONJUGATES INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2016-08-04 WO claimed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
US-12006311-B2 Compounds for use in preventing or treating cancer FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRONINSTITUT DE RECERCA (ES) 2024-06-11 US disclosed
WO-2024083861-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF SELABTEC SCIENCES, SLU (ES) 2024-04-25 WO disclosed
EP-4356909-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF Selabtec Sciences, SLU (ES) 2024-04-24 EP disclosed
EP-3645548-B1 METHODS FOR PREPARING BILE ACIDS MEDYTOX INC (KR) 2023-11-29 EP disclosed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
EP-3271468-B1 DEAMINATION OF ORGANOPHOSPHORUS-NUCLEOSIDES LABORATORIO TECNICO DE SEGURIDAD Y ESTANDARIZACION SL (ES) 2022-12-14 EP disclosed
EP-3813832-B1 COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER FUNDACIO HOSPITAL UNIV VALL DHEBRON INSTITUT DE RECERCA (ES) 2022-11-09 EP disclosed
WO-2008019784-A2 AVERMECTIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-02-21 WO disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 WO disclosed
WO-2006136309-A1 CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-12-28 WO disclosed
EP-1412346-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES Bayer CropScience AG (DE) 2004-04-28 EP disclosed
US-20040018598-A1 Bio-intermediates for use in the chemical synthesis of polyketides SANTI DANIEL (US) 2004-01-29 US disclosed
EP-1307579-A2 BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES Kosan Biosciences, Inc. (US) 2003-05-07 EP disclosed
WO-2003010155-A1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-02-06 WO disclosed
US-20020052028-A1 Bio-intermediates for use in the chemical synthesis of polyketides KOSAN BIOSCIENCES, INC. 2002-05-02 US disclosed
WO-2002012534-A2 BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES KOSAN BIOSCIENCES, INC. (US) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030065-A1 FLUORESCEIN POLYMER CONJUGATES PFAS, CD44, FGB ABL1 901/4885ABCB1 323/4885BCR 453/4885
US-20040018598-A1 Bio-intermediates for use in the chemical synthesis of polyketides DHPS, FDFT1, COASY ABL1 4748/4885ABCB1 1736/4885BCR 2016/4885
US-12006311-B2 Compounds for use in preventing or treating cancer UGT1A3, UGT1A1, UGT1A6 ABL1 2106/4885ABCB1 68/4885BCR 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.