Ethylenediamine

Ethylenediamine

SCHEMBL2494997

NCCN.O=C(O)C(O)(O)c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
HIF1A Q16665 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8790 0.89 CYP1A2 (0.54) CYP1A2CYP2D6MAPTKMT2AALDH1A1
SCHEMBL28062240 0.89 CYP1A2 (0.54) CYP1A2CYP2D6MAPTKMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL8592883 0.86 CYP1A2 (0.52) CYP1A2CYP2D6MAPTKMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL31621216 0.86 CYP1A2 (0.52) CYP1A2CYP2D6MAPTKMT2AALDH1A1
Ethylene SCHEMBL8590174 0.84 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL7519716 0.84 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2AALDH1A1
Benzylic Acid SCHEMBL11170094 0.81 CYP2C9 (0.59) KIF11CYP1A2CYP2D6MAPTKMT2A
Ethylenediamine SCHEMBL10608603 0.79 CYP1A2 (0.48) KIF11CYP1A2CYP2D6MAPTKMT2A
Ethylenediamine SCHEMBL27192522 0.79 CYP1A2 (0.48) KIF11CYP1A2CYP2D6MAPTKMT2A
Dopamine SCHEMBL1683080 0.78 KDM4E (0.60) CYP1A2CYP2D6MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3687953-B1 RETARDER FOR CALCIUM SULFOALUMINATE BELITE CEMENT HEIDELBERG MAT AG (DE) 2023-08-30 EP claimed
CN-112409070-A Ammonium phosphate water-soluble multi-element compound fertilizer and preparation process thereof 余隆 2021-02-26 CN claimed
EP-3687953-A1 RETARDER FOR CALCIUM SULFOALUMINATE BELITE CEMENT HeidelbergCement AG (DE) 2020-08-05 EP claimed
EP-3506762-A1 IMPROVED PRE-EMERGENT HERBICIDE W. Neudorff GmbH KG (DE) 2019-07-10 EP claimed
EP-3461800-A1 RETARDER FOR CALCIUM SULFOALUMINATE BELITE CEMENT HeidelbergCement AG (DE) 2019-04-03 EP claimed
CN-109006331-A A kind of implantation methods of the bletilla striata 广西陆川县兰辉农业科技有限公司 2018-12-18 CN claimed
CN-108863533-A Cold-resistant microbial liquid fertilizer and preparation method thereof 深圳市芭田生态工程股份有限公司 2018-11-23 CN claimed
CN-108410588-A A kind of environment-friendlytype type fabric cleaning stain remover and preparation method thereof 合肥佳洋电子科技有限公司 2018-08-17 CN claimed
WO-2018041916-A1 IMPROVED PRE-EMERGENT HERBICIDE W. NEUDORFF GMBH KG (DE) 2018-03-08 WO claimed
CN-106922464-A A kind of method for promoting cherry fruit coloring 金寨胜达农业科技有限公司 2017-07-07 CN claimed
EP-1467720-B1 DNA DOSAGE FORMS GLAXO GROUP LTD (GB) 2009-04-01 EP claimed
US-20080095854-A1 DNA DOSAGE FORMS GLAXO GROUP LIMITED 2008-04-24 US claimed
EP-1467711-B1 DNA DOSAGE FORMS GLAXO GROUP LTD (GB) 2007-03-21 EP claimed
US-20050085434-A1 Dna dosage forms GLAXO GROUP LIMITED (GB) 2005-04-21 US claimed
US-20050080028-A1 Ballast administering to mammals skins; high density core overcoated with amorphous reservoir containing dna; drug delivery; containing free radical scavenger GLAXO GROUP LIMITED (GB) 2005-04-14 US claimed
EP-1467720-A2 DNA DOSAGE FORMS GLAXO GROUP LIMITED (GB) 2004-10-20 EP claimed
EP-1467711-A2 DNA DOSAGE FORMS GLAXO GROUP LIMITED (GB) 2004-10-20 EP claimed
WO-2003061629-A2 DNA DOSAGE FORMS GLAXO GROUP LIMITED (GB) 2003-07-31 WO claimed
WO-2003061636-A2 DNA DOSAGE FORMS GLAXO GROUP LIMITED (GB) 2003-07-31 WO claimed
EP-1153901-A2 Composition for increasing the vegetable nutritional quality and the use thereof CONSORZIO PER LA PATATA TIPICA DI BOLOGNA (IT) 2001-11-14 EP claimed