Ethylenediamine

Ethylenediamine

SCHEMBL27192522

CC(O)(C(=O)O)c1ccccc1.CC(O)(C(=O)O)c1ccccc1.NCCN

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 2/20 0.47
HIF1A Q16665 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
CYP3A4 P08684 1/20 0.42
RECQL P46063 1/20 0.42
KIF11 P52732 6/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPK1 P28482 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL10608603 1.00 CYP1A2 (0.48) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL197251 0.89 MAPT (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL153694 0.89 MAPT (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL198241 0.89 MAPT (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL4326795 0.89 MAPT (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL21557850 0.89 MAPT (0.52) CYP1A2CYP2D6MAPTKMT2ACYP2C19
Iodide SCHEMBL3861799 0.87 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
Water SCHEMBL6414988 0.87 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
Water SCHEMBL7613695 0.87 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19
SCHEMBL31598893 0.87 CYP1A2 (0.50) CYP1A2CYP2D6MAPTKMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240114907-A1 STABILIZED CONAZOLE COMPOSITION UPL CORPORATION LTD (MU) 2024-04-11 US disclosed