SCHEMBL24950

SCHEMBL24950

O=C(O)/C=C/CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24951 1.00
SCHEMBL11470738 0.97
SCHEMBL27536198 0.78
SCHEMBL2997351 0.77
Bicarbonate SCHEMBL20291489 0.76 ALDH1A1 (0.39)
SCHEMBL1809605 0.76 TSHR (0.61)
SCHEMBL9726354 0.73 TSHR (0.58)
SCHEMBL273087 0.73 TSHR (0.58)
Ammonia Solution, Strong SCHEMBL38659341 0.73 TSHR (0.58)
SCHEMBL3065185 0.73 TSHR (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119890423-A Solid electrolyte of solid battery compound, composite electrolyte and environment-friendly utilization of battery 权冉(银川)科技有限公司 2025-04-25 CN claimed
CN-119650836-A Polymer solid-state battery electrolyte, solid-state lithium battery and method 权冉(银川)科技有限公司 2025-03-18 CN claimed
US-20130230559-A1 NOVEL TACROLIMUS ANALOGUES, A NEUROPROTECTIVE COMPOSITION COMPRISING THE SAME, AN IMMUNOSUPPRESSIVE COMPOSITION COMPRISING THE SAME, A METHOD FOR PREPARING THE SAME, AND A MUTANT FOR PRODUCING THE SAME Ewha University - Industry Collaboration Foundatio (KR) 2013-09-05 US claimed
WO-2012026665-A1 NOVEL TACROLIMUS DERIVATIVES, A NEUROPROTECTIVE COMPOSITION COMPRISING THE SAME, AN IMMUNOSUPPRESSIVE COMPOSITION COMPRISING THE SAME, A METHOD FOR PREPARING THE SAME, AND A MUTANT FOR PRODUCING THE SAME EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-01 WO claimed
EP-3746436-B1 FUSED RING COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-05-20 EP disclosed
CN-116829557-B Pentaheterocycle compound, preparation method and application thereof 上海艾力斯医药科技股份有限公司 2026-05-12 CN disclosed
US-12624053-B2 Ras inhibitors Revolution Medicines, Inc. (US) 2026-05-12 US disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20260070930-A1 RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2026-03-12 US disclosed
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 EP disclosed
US-20250388608-A1 RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2025-12-25 US disclosed
US-12441742-B2 Naphthyridine compounds as inhibitors of KRAS INCYTE CORPORATION (US) 2025-10-14 US disclosed
US-9505779-B2 Tacrolimus analogues, a neuroprotective composition comprising the same, an immunosuppressive composition comprising the same, a method for preparing the same, and a mutant for producing the same INTRON BIOTECHNOLOGY, INC. (KR) 2016-11-29 US disclosed
US-20150291554-A1 Bruton's Tyrosine Kinase Inhibitors PFIZER (US) 2015-10-15 US disclosed
EP-2914586-A1 BRUTON'S TYROSINE KINASE INHIBITORS Pfizer Inc. (US) 2015-09-09 EP disclosed
WO-2014068527-A1 BRUTON'S TYROSINE KINASE INHIBITORS PFIZER INC. (US) 2014-05-08 WO disclosed
US-20130230559-A1 NOVEL TACROLIMUS ANALOGUES, A NEUROPROTECTIVE COMPOSITION COMPRISING THE SAME, AN IMMUNOSUPPRESSIVE COMPOSITION COMPRISING THE SAME, A METHOD FOR PREPARING THE SAME, AND A MUTANT FOR PRODUCING THE SAME Ewha University - Industry Collaboration Foundatio (KR) 2013-09-05 US disclosed
WO-2012026665-A1 NOVEL TACROLIMUS DERIVATIVES, A NEUROPROTECTIVE COMPOSITION COMPRISING THE SAME, AN IMMUNOSUPPRESSIVE COMPOSITION COMPRISING THE SAME, A METHOD FOR PREPARING THE SAME, AND A MUTANT FOR PRODUCING THE SAME EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2012-03-01 WO disclosed
WO-2011153502-A2 ANTI-INFLAMMATORY AND QUORUM SENSING INHIBITION COMPOUNDS AND METHODS OF MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-12-08 WO disclosed
US-4325877-A Production of intermediates for enzyme inhibitors RICHARDSON-MERRELL INC. (US) 1982-04-20 US disclosed