Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115250 | 0.91 | CRBN (0.47) | CRBNDDB1HTT | |
| SCHEMBL24938771 | 0.88 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL26158809 | 0.87 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL24938746 | 0.84 | CRBN (0.53) | CRBNDDB1 | |
| SCHEMBL23115188 | 0.81 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL30922351 | 0.81 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL23115190 | 0.81 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL23115186 | 0.81 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL23115321 | 0.81 | CRBN (0.59) | CRBNDDB1 | |
| SCHEMBL26158808 | 0.81 | DDB1 (0.47) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122925-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | Medshine Discovery Inc. (CN) | 2023-01-25 | — | — | EP | disclosed |